Single Mutant Search

Single Mutant Search is a mutation-based search strategy that generates candidate pools by applying single-point mutations to existing sequences. This is particularly useful for local exploration around known high-performing sequences in protein engineering.

class alf_tools.optimizer.search.single_mutant_search.SingleMutantSearch(alphabet='ARNDCQEGHILKMFPSTWYV')

Bases: SearchProtocol

Search protocol for single mutant search.